Men who carry the BRCA2 gene variant and have a family history of prostate, breast, pancreatic or ovarian cancer will be offered a PSA test every two years between the ages of 45 and 61. The final recommendation follows a public consultation that received nearly 1,000 responses, with the programme expected to be rolling out in 2027.

Health and social care secretary, James Murray, said: ‘This is a major step forward in how we tackle prostate cancer - focusing on those most at risk, improving the treatments available, and backing the research we need to close the evidence gaps and save lives. 

‘We're following the science to make sure men get earlier answers and better care, and to avoid doing unnecessary harm.' 

The Government's £20m investment in prostate screening also includes the expansion of its TRANSFORM trial to all eligible Black men for the first time. 

TRANSFORM is jointly funded by Prostate Cancer UK and the National Institute for Health and Care Research.