The call for evidence will support the work of the newly formed National Commission into the Regulation of AI in Healthcare which brings together global AI leaders, clinicians, regulators and patient advocates and advises the MHRA on the future of health AI regulation.

Chief executive of the MHRA Lawrence Tallon said: ‘AI is already revolutionising our lives, both its possibilities and its capabilities are ever-expanding, and as we continue into this new world, we must ensure that its use in healthcare is safe, risk-proportionate and engenders public trust and confidence.  

‘The National Commission brings together a host of experts including patients' groups, clinicians, industry, academics and members from across government. Today we are asking the public to contribute by sharing their thoughts, experiences and opinions.

‘We want everyone to have the chance to help shape the safest and most advanced AI-enabled healthcare system in the world at this truly pivotal moment.'

Key themes of the consultation include: modernising the rules for AI in healthcare; keeping patients safe as AI evolves; and clarifying responsibility.

The call for evidence runs from Thursday 18 December 2025 to Monday 2nd February 2026.

The information gathered will help inform the commission's work and its recommendations to the MHRA in 2026.